Issue 52, 2020

Self-assembly of chimeric peptides toward molecularly defined hexamers with controlled multivalent ligand presentation

Abstract

This work demonstrates a self-assembling peptide strategy to form finite, molecularly defined trigonal bipyramidal-like hexamers which offer control over multivalent ligand display for enhanced tumor targeting.

Graphical abstract: Self-assembly of chimeric peptides toward molecularly defined hexamers with controlled multivalent ligand presentation

Supplementary files

Article information

Article type
Communication
Submitted
19 Mar 2020
Accepted
19 May 2020
First published
20 May 2020

Chem. Commun., 2020,56, 7128-7131

Author version available

Self-assembly of chimeric peptides toward molecularly defined hexamers with controlled multivalent ligand presentation

X. Yuan, L. Jiang, W. Chen, B. Song, W. Chen, X. Zuo, X. Sun, X. Li, K. Kirshenbaum, S. Luo and H. Dong, Chem. Commun., 2020, 56, 7128 DOI: 10.1039/D0CC02066D

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